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I 2019 udgav Sundhedsstyrelsen en national klinisk retningslinje (NKR) for opioidbehandling af kroniske nonmaligne smerter [13] (Tabel 1) og i samarbejde med Danske Regioner en ny smerteguide [fourteen]. I begge peges der på, at der skal tages individuelle hensyn, og at opioidbehandling kan anvendes til de undergrupper af patienter med smerter, hv

Leger i spesialisthelsetjenesten bør ikke rekvirere doser høyere enn 300 mg OMEQ for each døgn til pasienter i poliklinisk behandling ved langvarige smerter som ikke skyldes kreftsykdom.Generelt har medicin fra den tricykliske gruppe af antidepressiva større smertestillende effekt ved lavere dosis end SNRI præparater, Guys flere bivirkninger.D